INNOVATION
Platelet-Rich Plasma (PRP) therapy is a regenerative treatment that has gained traction in orthopedic and sports medicine for its potential to enhance tissue healing and reduce inflammation. By concentrating autologous (patient's own) platelets and their growth factors, PRP injections can promote cellular repair and modulate the inflammatory response in musculoskeletal injuries.
Clinical applications include chronic tendinopathies (e.g., lateral epicondylitis, Achilles, rotator cuff, gluteal, patellar tendinopathies), ligamentous injuries, muscle strains, and osteoarthritis in all joints, but most studied and confirmed efficacy in weight-bearing joints like the knee. While studies indicate PRP can improve pain and function, outcomes vary based on formulation techniques, patient selection, and disease severity. In particular, most recently actual platelet “dose” numbers are now considered one of the most important aspects to standardize to better promote efficacy.
As orthopedic providers, understanding PRP’s mechanism, indications, and patient-specific considerations is crucial in optimizing non-operative management strategies. Ongoing research continues to refine protocols and efficacy, making PRP a valuable adjunct to conventional therapies in musculoskeletal care.
